Effects of the chemomechanical stepping cycle on the traffic of molecular motors

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dc.creatorKlumpp, Stefan
dc.creatorChai, Yan
dc.creatorLipowsky, Reinhard
dc.date2008-10-09
dc.date.accessioned2026-07-07T10:08:42Z
dc.date.available2026-07-07T10:08:42Z
dc.descriptionWe discuss effects of the stepping kinetics of molecular motors on their traffic behavior on crowded filaments using a simple two-state chemomechanical cycle. While the general traffic behavior is quite robust with respect to the detailed kinetics of the step, a few observable parameters exhibit a strong dependence on these parameters. Most strikingly, the effective unbinding rate of the motors may both increase and decrease with increasing traffic density, depending on the details of the motor step. Likewise the run length either exhibits a strong decrease or almost no dependence on the traffic density. We compare our theoretical results with recent experimental observations on motor traffic.
dc.description14 pages, 3 figures
dc.identifierhttps://arxiv.org/abs/0810.1568
dc.identifierhttp://arxiv.org/abs/0810.1568
dc.identifierPhys. Rev. E 78, 041909 (2008)
dc.identifierdoi:10.1103/PhysRevE.78.041909
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/171088
dc.subjectStatistical Mechanics
dc.subjectSubcellular Processes
dc.titleEffects of the chemomechanical stepping cycle on the traffic of molecular motors
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