The age incidence of any cancer can be explained by a one-mutation model

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dc.creatorSchinazi, Rinaldo B.
dc.date2008-08-18
dc.date.accessioned2026-07-07T09:57:09Z
dc.date.available2026-07-07T09:57:09Z
dc.descriptionWe propose a one mutation model for cancer with a mutation rate that increases with time. Under rather general hypotheses the number of mutations is necessarily a (non homogeneous) Poisson process with the prescribed mutation rate. We show that the cumulative probability of cancer up to time $t$ is, up to a multiplicative constant, an antiderivative of the mutation rate.
dc.identifierhttps://arxiv.org/abs/0808.2424
dc.identifierhttp://arxiv.org/abs/0808.2424
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/167242
dc.subjectProbability
dc.subjectQuantitative Methods
dc.subject60K35,92D30
dc.titleThe age incidence of any cancer can be explained by a one-mutation model
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