Distributions of positron-emitting nuclei in proton and carbon-ion therapy studied with GEANT4

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dc.creatorPshenichnov, Igor
dc.creatorMishustin, Igor
dc.creatorGreiner, Walter
dc.date2006-08-02
dc.date2006-10-06
dc.date.accessioned2026-07-07T07:25:40Z
dc.date.available2026-07-07T07:25:40Z
dc.descriptionDepth distributions of positron-emitting nuclei in PMMA phantoms are calculated within a Monte Carlo model for Heavy-Ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.0). The calculated total production rates of $^{11}$C, $^{10}$C and $^{15}$O nuclei are compared with experimental data and with corresponding results of the FLUKA and POSGEN codes. The distributions of e$^+$ annihilation points are obtained by simulating radioactive decay of unstable nuclei and transporting positrons in surrounding medium. A finite spatial resolution of the Positron Emission Tomography (PET) is taken into account in a simplified way. Depth distributions of $β^+$-activity as seen by a PET scanner are calculated and compared to available data for PMMA phantoms. The calculated $β^+$-activity profiles are in good agreement with PET data for proton and $^{12}$C beams at energies suitable for particle therapy. The MCHIT capability to predict the $β^+$-activity and dose distributions in tissue-like materials of different chemical composition is demonstrated.
dc.description16 pages, 4 figures
dc.identifierhttps://arxiv.org/abs/physics/0608017
dc.identifierhttp://arxiv.org/abs/physics/0608017
dc.identifierPhys. Med. Biol. 51 (2006) 6099-6112
dc.identifierdoi:10.1088/0031-9155/51/23/011
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/116800
dc.subjectMedical Physics
dc.titleDistributions of positron-emitting nuclei in proton and carbon-ion therapy studied with GEANT4
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