Interactions Between Stably Rolling Leukocytes In Vivo

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We have characterized the two-dimensional spatial dependence of the hydrodynamic interactions between two adhesively rolling leukocytes in a live venule in the mouse cremaster muscle. Two rolling leukocytes were observed to slow each other down when rolling together in close proximity, due to mutual sheltering from the external blood flow in the vessel lumen. These results are in agreement with a previous study of leukocyte rolling interactions using carbohydrate-coated beads in a parallel-plate flow chamber and a detailed computer model of adhesion in a multicellular environment.
9 pages, 2 figures, submitted as Brief Report to Phys. Rev. E

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Biological Physics, Fluid Dynamics, Cell Behavior

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http://salesiana.dossiersoluciones.com/handle/123456789/85657

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/physics/0310082
 http://arxiv.org/abs/physics/0310082

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arXiv