The Neighbor-Net Algorithm

dc.creatorLevy, Dan
dc.creatorPachter, Lior
dc.date2007-02-18
dc.date2008-05-12
dc.date.accessioned2026-07-07T09:38:27Z
dc.date.available2026-07-07T09:38:27Z
dc.descriptionThe neighbor-joining algorithm is a popular phylogenetics method for constructing trees from dissimilarity maps. The neighbor-net algorithm is an extension of the neighbor-joining algorithm and is used for constructing split networks. We begin by describing the output of neighbor-net in terms of the tessellation of $\bar{\MM}_{0}^n(\mathbb{R})$ by associahedra. This highlights the fact that neighbor-net outputs a tree in addition to a circular ordering and we explain when the neighbor-net tree is the neighbor-joining tree. A key observation is that the tree constructed in existing implementations of neighbor-net is not a neighbor-joining tree. Next, we show that neighbor-net is a greedy algorithm for finding circular split systems of minimal balanced length. This leads to an interpretation of neighbor-net as a greedy algorithm for the traveling salesman problem. The algorithm is optimal for Kalmanson matrices, from which it follows that neighbor-net is consistent and has optimal radius 1/2. We also provide a statistical interpretation for the balanced length for a circular split system as the length based on weighted least squares estimates of the splits. We conclude with applications of these results and demonstrate the implications of our theorems for a recently published comparison of Papuan and Austronesian languages.
dc.identifierhttps://arxiv.org/abs/math/0702515
dc.identifierhttp://arxiv.org/abs/math/0702515
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/160811
dc.subjectCombinatorics
dc.subjectQuantitative Methods
dc.titleThe Neighbor-Net Algorithm
dc.typetext

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