Optimized free energies from bidirectional single-molecule force spectroscopy

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dc.creatorMinh, David D. L.
dc.creatorAdib, Artur B.
dc.date2008-02-02
dc.date2008-04-10
dc.date.accessioned2026-07-07T09:37:11Z
dc.date.available2026-07-07T09:37:11Z
dc.descriptionAn optimized method for estimating path-ensemble averages using data from processes driven in opposite directions is presented. Based on this estimator, bidirectional expressions for reconstructing free energies and potentials of mean force from single-molecule force spectroscopy - valid for biasing potentials of arbitrary stiffness - are developed. Numerical simulations on a model potential indicate that these methods perform better than unidirectional strategies.
dc.description4 pages, 2 figures
dc.identifierhttps://arxiv.org/abs/0802.0224
dc.identifierhttp://arxiv.org/abs/0802.0224
dc.identifierPhys. Rev. Lett. 100, 180602 (2008)
dc.identifierdoi:10.1103/PhysRevLett.100.180602
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/160369
dc.subjectStatistical Mechanics
dc.titleOptimized free energies from bidirectional single-molecule force spectroscopy
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