A mathematical model for the germinal center morphology and affinity maturation

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dc.creatorMeyer-Hermann, Michael
dc.date2002-03-07
dc.date.accessioned2026-07-07T05:47:09Z
dc.date.available2026-07-07T05:47:09Z
dc.descriptionDuring germinal center reactions the appearance of two specific zones is observed: the dark and the light zone. Up to now, the origin and function of these zones are poorly understood. In the framework of a stochastic and discrete model several possible pathways of zone development during germinal center reactions are investigated. The importance of the zones in the germinal center for affinity maturation, i.e. the process of antibody optimization is discussed.
dc.description64 pages, 12 figures, accepted for publication in J. Theor. Biol
dc.identifierhttps://arxiv.org/abs/physics/0203021
dc.identifierhttp://arxiv.org/abs/physics/0203021
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/84600
dc.subjectBiological Physics
dc.subjectCell Behavior
dc.titleA mathematical model for the germinal center morphology and affinity maturation
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