Non-equilibrium behavior of lysozyme solutions: beads, clusters and gels
Loading...
Date
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Description
Observation of salt-induced aggregation of lysozyme at pH = 4.5, 22$^{\circ}$C by optical microscopy revealed four regimes: bicontinuous texture, `beads', large aggregates, and transient gelation. The interaction of a metastable liquid-liquid binodal and an ergodic to non-ergodic transition boundary inside the equilibrium crystallization region can explain our findings. Lysozyme data at -2$^{\circ}$C, as well as many literature results, are consistent with the relative movement of these boundaries.
4 pages, 4 figures
4 pages, 4 figures