Dynamical investigation of macromolecular hybridization bioassays

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A novel sensoric technique for the dynamical in situ investigation of a hybridization bio assay is presented, which utilizes a metal bead labeling method. Therein, hybridization results in an increased metal coverage on parts of a substrate, where it takes place. Our sensing principle relies on the measurement of the radio frequency impedance of the hybridization spots. We propose several examples for sensor devices.

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Instrumentation and Detectors, Biological Physics, Quantitative Biology

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http://salesiana.dossiersoluciones.com/handle/123456789/84810

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/physics/0207064
 http://arxiv.org/abs/physics/0207064

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arXiv