3He Lung Imaging in an Open Access, Very-Low-Field Human MRI System

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dc.creatorMair, R. W.
dc.creatorHrovat, M. I.
dc.creatorPatz, S.
dc.creatorRosen, M. S.
dc.creatorRuset, I. C.
dc.creatorTopulos, G. P.
dc.creatorTsai, L. L.
dc.creatorButler, J. P.
dc.creatorHersman, F. W.
dc.creatorWalsworth, R. L.
dc.date2004-03-18
dc.date2004-12-16
dc.date.accessioned2026-07-07T05:51:31Z
dc.date.available2026-07-07T05:51:31Z
dc.descriptionThe human lung and its functions are extremely sensitive to gravity, however the conventional high-field magnets used for most laser-polarized 3He MRI of the human lung restrict subjects to lying horizontally. Imaging of human lungs using inhaled laser-polarized 3He gas is demonstrated in an open-access very-low-magnetic-field (< 5 mT) MRI instrument. This prototype device employs a simple, low-cost electromagnet, with an open geometry that allows variation of the orientation of the imaging subject in a two-dimensional plane. As a demonstration, two-dimensional lung images were acquired with 4 mm in-plane resolution from a subject in two orientations: lying supine, and sitting in a vertical position with one arm raised. Experience with this prototype device will guide optimization of a second-generation very-low-field imager to enable studies of human pulmonary physiology as a function of subject orientation.
dc.descriptionsingle pdf file, approx 19 pages double spaced, including 3 figures. accepted for publication in Magnetic Resonance in Medicine. Magnetic Resonance in Medicine, accepted for publication 2004
dc.identifierhttps://arxiv.org/abs/physics/0403090
dc.identifierhttp://arxiv.org/abs/physics/0403090
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/86012
dc.subjectMedical Physics
dc.subjectInstrumentation and Detectors
dc.title3He Lung Imaging in an Open Access, Very-Low-Field Human MRI System
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