The role of synaptic facilitation in coincidence spike detection
| dc.creator | Mejias, Jorge F. | |
| dc.creator | Torres, Joaquin J. | |
| dc.date | 2006-05-03 | |
| dc.date.accessioned | 2026-07-07T07:15:11Z | |
| dc.date.available | 2026-07-07T07:15:11Z | |
| dc.description | Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal coincidences of spikes arriving at certain frequency from N different afferents. We extend a previous work that only considers synaptic depression as the most important mechanism in the transmission of information through synapses, to a more general situation including also synaptic facilitation. Our study shows that: 1) facilitation enhances the detection of correlated signals arriving from a subset of presynaptic excitatory neurons, with different degrees of correlation among this subset, and 2) the presence of facilitation allows for a better detection of firing rate changes. Finally, we also observed that facilitation determines the existence of an optimal input frequency which allows the best performance for a wide (maximum) range of the neuron firing threshold. This optimal frequency can be controlled by means of facilitation parameters. | |
| dc.description | 19 pages, 8 figures | |
| dc.identifier | https://arxiv.org/abs/q-bio/0605006 | |
| dc.identifier | http://arxiv.org/abs/q-bio/0605006 | |
| dc.identifier.uri | http://salesiana.dossiersoluciones.com/handle/123456789/113172 | |
| dc.subject | Neurons and Cognition | |
| dc.title | The role of synaptic facilitation in coincidence spike detection | |
| dc.type | text |