Temperature- and Force-Induced beta-Sheet Unfolding in an Exactly Solvable Model
| dc.creator | Zhou, Haijun | |
| dc.date | 2001-12-06 | |
| dc.date | 2002-03-18 | |
| dc.date.accessioned | 2026-07-07T02:43:45Z | |
| dc.date.available | 2026-07-07T02:43:45Z | |
| dc.description | The stability of a $β$-sheeted conformation and its transition into a random coil are studied with a 2D lattice biopolymer model. At low temperature and low external force, the polymer folds back and forth on itself and forms a $β$-sheet. Our analytical calculation and Monte Carlo simulation reveal that a co-operative $β$-sheet--random coil transition takes places when the temperature or force is increased, with a dramatic decrease in the contact number. These predictions are in good agreement with experiments on titin protein. This transition is not a real phase-transition, indicating that backbone hydrogen-bonding alone is unable to stabilize a distinct $β$-sheet phase. | |
| dc.description | 13 pages with 4 ps figures. Revised version. A serious mistake in the original version was corrected and new simulation data were included | |
| dc.identifier | https://arxiv.org/abs/cond-mat/0112090 | |
| dc.identifier | http://arxiv.org/abs/cond-mat/0112090 | |
| dc.identifier.uri | http://salesiana.dossiersoluciones.com/handle/123456789/18620 | |
| dc.subject | Soft Condensed Matter | |
| dc.subject | Statistical Mechanics | |
| dc.subject | Quantitative Biology | |
| dc.title | Temperature- and Force-Induced beta-Sheet Unfolding in an Exactly Solvable Model | |
| dc.type | text |