Acoustic "distributed source" mixing of smallest fluid volumes
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Acoustically driven mixing of small fluid volumes is reported. Using surface acoustic waves on a mixer chip, conversion of those into bulk waves, and employing wave guiding effects enables us to distribute a set of "virtual sources" for acoustic streaming over large areas. we demonstrate the applicability of our mixing technique to micro array applications, for mixing of individual wells in a micro titer plate, and other state-of-the-art hybridization assays.