A pseudo active kinematic constraint for a biological living soft tissue: an effect of the collagen network

dc.creatorBourdarias, Christian
dc.creatorGerbi, Stéphane
dc.creatorOhayon, Jacques
dc.date2008-12-03
dc.date.accessioned2026-07-07T12:09:03Z
dc.date.available2026-07-07T12:09:03Z
dc.descriptionRecent studies in mammalian hearts show that left ventricular wall thickening is an important mechanism for systolic ejection and that during contraction the cardiac muscle develops significant stresses in the muscular cross-fiber direction. We suggested that the collagen network surrounding the muscular fibers could account for these mechanical behaviors. To test this hypothesis we develop a model for large deformation response of active, incompressible, nonlinear elastic and transversely isotropic living soft tissue (such as cardiac or arteries tissues) in which we include a coupling effect between the connective tissue and the muscular fibers. Then, a three-dimensional finite element formulation including this internal pseudo-active kinematic constraint is derived. Analytical and finite element solutions are in a very good agreement. The numerical results show this wall thickening effect with an order of magnitude compatible with the experimental observations.
dc.identifierhttps://arxiv.org/abs/0812.0666
dc.identifierhttp://arxiv.org/abs/0812.0666
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/209498
dc.subjectAnalysis of PDEs
dc.subjectClassical Physics
dc.subjectMedical Physics
dc.subjectTissues and Organs
dc.titleA pseudo active kinematic constraint for a biological living soft tissue: an effect of the collagen network
dc.typetext

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