Multi-Stability in Monotone Input/Output Systems

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This paper studies the emergence of multi-stability and hysteresis in those systems that arise, under positive feedback, starting from monotone systems with well-defined steady-state responses. Such feedback configurations appear routinely in several fields of application, and especially in biology. Characterizations of global stability behavior are stated in terms of easily checkable graphical conditions. An example of a signaling cascade under positive feedback is presented.
See http://www.math.rutgers.edu/~sontag for related work; to appear in Systems and Control Letters

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Quantitative Methods, Molecular Networks

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http://salesiana.dossiersoluciones.com/handle/123456789/88130

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/q-bio/0309002
 http://arxiv.org/abs/q-bio/0309002

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arXiv