On the Hypercube Structure of the Genetic Code

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dc.creatorJimenez-Montano, Miguel A.
dc.creatorde la Mora-Basanez, Carlos R.
dc.creatorPoeschel, Thorsten
dc.date2002-04-02
dc.date.accessioned2026-07-07T02:44:52Z
dc.date.available2026-07-07T02:44:52Z
dc.descriptionA representation of the genetic code as a six-dimensional Boolean hypercube is proposed. It is assumed here that this structure is the result of the hierarchical order of the interaction energies of the bases in codon-anticodon recognition. The proposed structure demonstrates that in the genetic code there is a balance between conservatism and innovation. Comparing aligned positions in homologous protein sequences two different behaviors are found: a) There are sites in which the different amino acids present may be explained by one or two "attractor nodes" (coding for the dominating amino acid(s)) and their one-bit neighbors in the codon hypercube, and b) There are sites in which the amino acids present correspond to codons located in closed paths in the hypercube. The structure of the code facilitates evolution: the variation found at the variable positions of proteins do not corresponds to random jumps at the codon level, but to well defined regions of the hypercube.
dc.description14 pages, 7 figures
dc.identifierhttps://arxiv.org/abs/cond-mat/0204044
dc.identifierhttp://arxiv.org/abs/cond-mat/0204044
dc.identifierIn H.A.Lim and C.A.Cantor (eds.), Proc. Bioinformatics and Genome Research, p. 445 (World Scientific, 1994)
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/19107
dc.subjectSoft Condensed Matter
dc.subjectGenomics
dc.titleOn the Hypercube Structure of the Genetic Code
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