2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/184724The isoscaling behavior is investigated in the frame of Isospin dependent Quantum Molecular Dynamics (IQMD) models. The isotopic yields ratio $Y_2$/$Y_1$ for reactions $^{48}Ca$+$^{48}Ca$ and $^{40}Ca+^{40}Ca$ at different entrance channels are simulated and presented, the relationship between the isoscaling parameter and the entrance channel is analyzed, the results show that $α$ and $β$ reduce with the rise of incident energies and increase with the impact parameter b, which can be attributed to the temperature varying of the pre-fragments in different entrance channels. The relation of $α$ and symmetry-term coefficient $C_{sym}$ reveals that the chemical potential difference $\triangleμ$ is sensitive to the symmetry-term coefficient $C_{sym}$.4 pages, 4 figures; revised version to Chinese Physics LettersNuclear TheoryNuclear Experimenttext