2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/121644We made a link between Extra Cellular Matrix (ECM) plasticity and the morphologi cal changes in synapses after synaptic excitation. A recent study by Zhang et al \cite{zhang} showed tha t transmembrane voltage causes movement of the cell membrane. Here we will study the relation between th e mechanical properties of collagen which is the major component of the ECM and synaptic morphological c hanges in relation with the theory of DO Hebb \cite{hebb}5pages no figureSoft Condensed MatterOther Condensed Mattertext