2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/151824We present a statistical mechanics approach to the protein folding problem. We first review some of the basic properties of proteins, and introduce some physical models to describe their thermodynamics. These models rely on a random heteropolymeric description of these non random biomolecules. Various kinds of randomness are investigated, and the connection with disordered systems is discussed. We conclude by a brief study of the dynamics of proteins.57 pages, 7 figures. Uses lprocl.sty (included). To appear in " Spin glasses and random fields ", A.P. Young (ed.), World ScientificDisordered Systems and Neural NetworksSoft Condensed MatterQuantitative Biologytext