2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/68846Results on characterization of manifolds in terms of certain Lie algebras growing on them, especially Lie algebras of differential operators, are reviewed and extended. In particular, we prove that a smooth (real-analytic, Stein) manifold is characterized by the corresponding Lie algebra of linear differential operators, i.e. isomorphisms of such Lie algebras are induced by the appropriate class of diffeomorphisms of the underlaying manifolds.15 pagesDifferential Geometry17B63; 13N10; 16S32; 17B40; 17B65; 53D17text