2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/194032The abundance of Li, Be, and B isotopes in galactic cosmic rays (GCR) between E=50-200 MeV/nucleon has been observed by the Cosmic Ray Isotope Spectrometer (CRIS) on NASA's ACE mission since 1997 with high statistical accuracy. Precise observations of Li, Be, B can be used to constrain GCR propagation models. \iffalse Precise observations of Li, Be, and B in addition to well-measured production cross-sections are used to further constrain GCR propagation models. \fi We find that a diffusive reacceleration model with parameters that best match CRIS results (e.g. B/C, Li/C, etc) are also consistent with other GCR observations. A $\sim$15--20% overproduction of Li and Be in the model predictions is attributed to uncertainties in the production cross-section data. The latter becomes a significant limitation to the study of rare GCR species that are generated predominantly via spallation.9 pages of TeX format with three figures. Accepted for publication to Advances in Space Research (Elsevier)AstrophysicsObservations of the Li, Be, and B isotopes and constraints on cosmic-ray propagationtext