2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/87421We compare numerically the effectiveness of three recently proposed algorithms, multicanonical simulations, simulations in a 1/k-ensemble, and simulated tempering for the protein folding problem. For this we perform simulations with high statistics for one of the simplest peptides, Met-enkephalin. While the performances of all three approaches is much better than traditional methods, we find that the differences among the three are only marginal.Latex, no figures include, for reprints send e-mail to authorsChemical PhysicsCondensed MatterBiological PhysicsComputational PhysicsQuantitative Biologytext