2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/105335We investigate a mechanism for the robust identification of the center of a developing biological system. We assume the existence of two morphogen gradients, an activator emanating from the anterior, and a co-repressor from the posterior. The co-repressor inhibits the action of the activator in switching on target genes. We apply this system to Drosophila embryos, where we predict the existence of a hitherto undetected posterior co-repressor. Using mathematical modelling, we show that a symmetric activator-co-repressor model can quantitatively explain the precise mid-embryo expression boundary of the hunchback gene, and the scaling of this pattern with embryo size.4 pages, 3 figuresTissues and OrgansOther Condensed MatterStatistical MechanicsOther Quantitative Biologytext