2026-07-072026-07-07http://salesiana.dossiersoluciones.com/handle/123456789/100046A balance is described with Langmuir binding of weights to each side. This simple physical system, when coupled with a previously derived equation for the equivalent displacement of weight that perturbs the equilibrium of a balance, models two-state, receptor systems in pharmacology for receptor activation. Surprisingly, this system also shows desensitization similar to many drug-receptor systems. Although understanding the biophysics behind receptor signaling is an important endeavor by itself, this analogy with a simple balance may bring new insights into other areas of physics as well.11 pages with 3 embedded figuresBiological PhysicsQuantitative Methodstext