Enhancing protein drop stability for crystallization by chemical patterning

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dc.creatorBerejnov, Viatcheslav
dc.creatorThorne, Robert E.
dc.date2006-04-12
dc.date.accessioned2026-07-07T07:05:28Z
dc.date.available2026-07-07T07:05:28Z
dc.descriptionMotion of protein drops on crystallization media during routine handling is a major factor affecting the reproducibility of crystallization conditions. Drop stability can be enhanced by chemical patterning to more effectively pin the drop's contact line. As an example, a hydrophilic area is patterned on an initially flat hydrophobic glass slide. The drop remains confined to the hydrophilic area, and the maximum drop size that remains stable when the slide is rotated to the vertical position increases. This simple method is readily scalable and has the potential to significantly improve outcomes in hanging and sitting drop crystallization.
dc.descriptiontext 4 pages, 6 jpg figures
dc.identifierhttps://arxiv.org/abs/cond-mat/0604326
dc.identifierhttp://arxiv.org/abs/cond-mat/0604326
dc.identifierActa Crystallographica Section D (2005) 61, 1563
dc.identifierdoi:10.1107/S0907444905028866
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/109682
dc.subjectSoft Condensed Matter
dc.subjectMaterials Science
dc.titleEnhancing protein drop stability for crystallization by chemical patterning
dc.typetext

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