Adhesion of membranes via actively switched receptors

Thumbnail Image

Date

Authors

Journal Title

Journal ISSN

Volume Title

Publisher

Abstract

Description

We consider a theoretical model for membranes with adhesive receptors, or stickers, that are actively switched between two conformational states. In their 'on'-state, the stickers bind to ligands in an apposing membrane, whereas they do not interact with the ligands in their 'off'-state. We show that the adhesiveness of the membranes depends sensitively on the rates of the conformational switching process. This dependence is reflected in a resonance at intermediate switching rates, which can lead to large membrane separations and unbinding. Our results may provide insights into novel mechanisms for the controlled adhesion of biological or biomimetic membranes.
5 pages, 6 figures; to appear in Physical Review Letters

Keywords

Soft Condensed Matter, Statistical Mechanics, Subcellular Processes

Citation

URI

http://salesiana.dossiersoluciones.com/handle/123456789/105636

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/cond-mat/0512514
 http://arxiv.org/abs/cond-mat/0512514

Collections

arXiv