Adhesion of membranes via actively switched receptors

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dc.creatorRozycki, Bartosz
dc.creatorLipowsky, Reinhard
dc.creatorWeikl, Thomas R.
dc.date2005-12-20
dc.date.accessioned2026-07-07T06:53:35Z
dc.date.available2026-07-07T06:53:35Z
dc.descriptionWe consider a theoretical model for membranes with adhesive receptors, or stickers, that are actively switched between two conformational states. In their 'on'-state, the stickers bind to ligands in an apposing membrane, whereas they do not interact with the ligands in their 'off'-state. We show that the adhesiveness of the membranes depends sensitively on the rates of the conformational switching process. This dependence is reflected in a resonance at intermediate switching rates, which can lead to large membrane separations and unbinding. Our results may provide insights into novel mechanisms for the controlled adhesion of biological or biomimetic membranes.
dc.description5 pages, 6 figures; to appear in Physical Review Letters
dc.identifierhttps://arxiv.org/abs/cond-mat/0512514
dc.identifierhttp://arxiv.org/abs/cond-mat/0512514
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/105636
dc.subjectSoft Condensed Matter
dc.subjectStatistical Mechanics
dc.subjectSubcellular Processes
dc.titleAdhesion of membranes via actively switched receptors
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