Optimal length and signal amplification in weakly activated signal transduction cascades

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dc.creatorChaves, Madalena
dc.creatorSontag, Eduardo D.
dc.creatorDinerstein, Robert J.
dc.date2003-11-20
dc.date.accessioned2026-07-07T05:03:05Z
dc.date.available2026-07-07T05:03:05Z
dc.descriptionWeakly activated signaling cascades can be modeled as linear systems. The input-to-output transfer function and the internal gain of a linear system, provide natural measures for the propagation of the input signal down the cascade and for the characterization of the final outcome. The most efficient design of a cascade for generating sharp signals, is obtained by choosing all the off rates equal, and a ``universal'' finite optimal length.
dc.description27 pages, 10 figures, LaTeX file
dc.identifierhttps://arxiv.org/abs/math/0311357
dc.identifierhttp://arxiv.org/abs/math/0311357
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/69275
dc.subjectOptimization and Control
dc.subjectMolecular Networks
dc.subject93D25, 93B99, 92C99
dc.titleOptimal length and signal amplification in weakly activated signal transduction cascades
dc.typetext

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