VE-cadherin and claudin-5: it takes two to tango

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dc.creatorGavard, Julie
dc.creatorGutkind, J Silvio
dc.date2008-11-25
dc.date.accessioned2026-07-07T10:36:30Z
dc.date.available2026-07-07T10:36:30Z
dc.descriptionEndothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively. Emerging evidence suggests that VE-cadherin controls claudin-5 expression by preventing the nuclear accumulation of FoxO1 and -catenin, which repress the claudin-5 promoter. This indicates that a crosstalk mechanism operates between these junctional structures.
dc.identifierhttps://arxiv.org/abs/0811.4025
dc.identifierhttp://arxiv.org/abs/0811.4025
dc.identifierNat Cell Biol 10, 8 (2008) 883-5
dc.identifierdoi:10.1038/ncb0808-883
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/180072
dc.subjectCell Behavior
dc.titleVE-cadherin and claudin-5: it takes two to tango
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