Sensitivity Analysis of Stoichiometric Networks: An Extension of Metabolic Control Analysis to Non-equilibrium Trajectories

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dc.creatorIngalls, Brian P.
dc.creatorSauro, Herbert M.
dc.date2002-06-20
dc.date.accessioned2026-07-07T05:47:44Z
dc.date.available2026-07-07T05:47:44Z
dc.descriptionA sensitivity analysis of general stoichiometric networks is considered. The results are presented as a generalization of Metabolic Control Analysis, which has been concerned primarily with system sensitivities at steady state. An expression for time-varying sensitivity coefficients is given, and the Summation and Connectivity Theorems are generalized. The results are compared to previous treatments. The analysis is accompanied by a discussion of the computation of the sensitivity coefficients and an application to a model of phototransduction.
dc.description23 pages, 13 figures
dc.identifierhttps://arxiv.org/abs/physics/0206075
dc.identifierhttp://arxiv.org/abs/physics/0206075
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/84767
dc.subjectBiological Physics
dc.subjectQuantitative Biology
dc.titleSensitivity Analysis of Stoichiometric Networks: An Extension of Metabolic Control Analysis to Non-equilibrium Trajectories
dc.typetext

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