First passage times of pulling-assisted DNA unzipping

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dc.creatorLakatos, G.
dc.creatorChou, T.
dc.creatorBergersen, B.
dc.creatorPatey, G.
dc.date2004-06-01
dc.date.accessioned2026-07-07T02:58:25Z
dc.date.available2026-07-07T02:58:25Z
dc.descriptionWe investigate the voltage-driven transport of hybridized DNA through membrane channels. As membrane channels are typically too narrow to accommodate hybridized DNA, the dehybridization of the DNA is the critical rate limiting step in the transport process. Using a two-dimensional stochastic model, we show that the dehybridization process proceeds by two distinct mechanisms; thermal denaturation in the limit of low driving voltage, and direct stripping in the high to moderate voltage regime. Additionally, we investigate the effects of introducing non-homologous defects into the DNA strand.
dc.description7pp, 3 figures
dc.identifierhttps://arxiv.org/abs/cond-mat/0406006
dc.identifierhttp://arxiv.org/abs/cond-mat/0406006
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/24079
dc.subjectStatistical Mechanics
dc.subjectSoft Condensed Matter
dc.titleFirst passage times of pulling-assisted DNA unzipping
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