Cable dynamics applied to long-length scale mechanics of DNA

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dc.creatorGoyal, Sachin
dc.creatorLillian, Todd
dc.creatorPerkins, Noel C.
dc.creatorMeyhofer, Edgar
dc.date2007-02-23
dc.date.accessioned2026-07-07T07:48:31Z
dc.date.available2026-07-07T07:48:31Z
dc.descriptionThis paper introduces the use of cable dynamics models as a means to explore the mechanics of DNA on long-length scales. It is on these length scales that DNA forms twisted and curved three-dimensional shapes known as supercoils and loops. These long-length scale DNA structures have a pronounced influence on the functions of this molecule within the cell including the packing of DNA in the cell nucleus, transcription, replication and gene repair. We provide a short background to the mechanics of DNA and suggest the logical connection to the mechanics of a low tension cable. A computational model is then summarized and example results are presented for DNA supercoiling and looping.
dc.description14 pages, 7 figures, An invited keynote speech, in CD-ROM Proceedings of Sixth International Symposium on Cable Dynamics, Charleston, SC, 19-22 Sept, 2005
dc.identifierhttps://arxiv.org/abs/physics/0702197
dc.identifierhttp://arxiv.org/abs/physics/0702197
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/124527
dc.subjectBiological Physics
dc.subjectChemical Physics
dc.subjectComputational Physics
dc.titleCable dynamics applied to long-length scale mechanics of DNA
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